CIQUIBIC was originated on the basis of the Departamento de Química Biológica of Facultad de Ciencias Químicas. It was founded in 1963 by Professor Dr. Ranwel Caputto (1916-1994), who was a close collaborator of Dr. Luis F. Leloir, Nobel Price in Chemistry, 1970. Nowadays it is properly equipped for research activities in biochemistry, biophysics, and molecular and cell biology. Besides minor equipment and facilities that belong to each research group, CIQUBIC counts with the following general equipment: ultracentrifuges (3), refigerated centrifuges (3), scintillation counter (3), differential scanning colorimeter(1), fluorometer (1), spectrophotometer (3), IR spectrophotometer, monolayers equipment, HPLC, fast chromatography, electrophoresis equipments, cold chamber, freezers, phosphorimager, network of 40 PCs with internet access, etc. As central facilities, there is a bioterium, a cell culture laboratory, (100m2), advanced optic microscopy laboratory equipped with a confocal microscope (shared with the Research Institute Mercedes and Martín Ferreyra-CONICET), 3 fluorescence microscopes, micromanipulator, cell micro-injector, CCD photographic cameras, software for image analysis (Metamorph), etc. The covered surface available for this Centre is detailed below.